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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XIAP
All Species:
2.12
Human Site:
T356
Identified Species:
4.24
UniProt:
P98170
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98170
NP_001158.2
497
56685
T356
E
E
C
L
V
R
T
T
E
K
T
P
S
L
T
Chimpanzee
Pan troglodytes
Q95M72
236
27118
L115
T
I
F
P
N
P
M
L
Q
E
A
I
R
M
G
Rhesus Macaque
Macaca mulatta
XP_001114854
292
33120
Q171
E
A
R
L
K
S
F
Q
N
W
P
D
Y
A
H
Dog
Lupus familis
XP_538165
615
69039
A474
S
E
W
I
L
R
T
A
E
R
T
R
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60989
496
56061
A355
E
E
S
L
G
R
T
A
E
K
T
P
S
L
T
Rat
Rattus norvegicus
Q9R0I6
496
56054
A355
G
E
S
V
V
R
T
A
E
K
T
P
S
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509526
607
68021
T351
L
L
E
Q
L
L
S
T
S
D
T
P
V
D
E
Chicken
Gallus gallus
Q90660
611
68991
T355
L
L
W
N
S
S
C
T
T
S
D
K
P
V
D
Frog
Xenopus laevis
A5D8Q0
488
55110
E354
L
H
K
A
N
S
G
E
A
S
P
A
L
P
K
Zebra Danio
Brachydanio rerio
NP_919377
405
45574
H284
D
E
D
P
W
E
E
H
A
R
H
Y
P
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24307
498
54520
G347
Q
R
K
L
L
S
S
G
C
A
F
S
T
L
D
Honey Bee
Apis mellifera
XP_396819
518
59795
D372
L
E
I
G
L
H
I
D
R
V
K
R
A
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
57.7
70.2
N.A.
89.1
89.7
N.A.
28.6
29.6
50
39.4
N.A.
33.7
35.3
N.A.
N.A.
Protein Similarity:
100
44.2
58.1
74.6
N.A.
94.1
95.5
N.A.
45.6
45.1
69.6
56.7
N.A.
51.2
54.4
N.A.
N.A.
P-Site Identity:
100
0
13.3
53.3
N.A.
80
66.6
N.A.
20
6.6
0
6.6
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
20
13.3
73.3
N.A.
80
80
N.A.
33.3
13.3
0
20
N.A.
40
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
25
17
9
9
9
9
9
0
% A
% Cys:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
9
% C
% Asp:
9
0
9
0
0
0
0
9
0
9
9
9
0
9
17
% D
% Glu:
25
50
9
0
0
9
9
9
34
9
0
0
0
0
9
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
9
9
0
9
9
0
0
0
0
0
9
9
% G
% His:
0
9
0
0
0
9
0
9
0
0
9
0
0
0
9
% H
% Ile:
0
9
9
9
0
0
9
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
17
0
9
0
0
0
0
25
9
9
0
0
17
% K
% Leu:
34
17
0
34
34
9
0
9
0
0
0
0
9
42
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
17
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
0
9
0
0
0
0
17
34
17
9
0
% P
% Gln:
9
0
0
9
0
0
0
9
9
0
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
34
0
0
9
17
0
17
9
0
0
% R
% Ser:
9
0
17
0
9
34
17
0
9
17
0
9
34
0
0
% S
% Thr:
9
0
0
0
0
0
34
25
9
0
42
0
9
0
34
% T
% Val:
0
0
0
9
17
0
0
0
0
9
0
0
9
17
0
% V
% Trp:
0
0
17
0
9
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _